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Gynostemma pentaphyllum (GP) and Superoxide Dismutase (SOD)

Authors: Chi and colleagues Source: Abstract: In a study published in 2012, Chi and colleagues tried to investigate the effects of polysaccharide from Gynostemma pentaphyllum on antioxidant activity in skeletal muscle of mice exercised to exhaustion. Researchers used a forced swim test of mice and determined the levels of glucose, glutathione peroxidase, superoxide dismutase and other markers. They found increased antioxidant enzyme activities due to the increased levels of SOD. (10) Another animal study examined the protective effects of gypenosides from…

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Chemical constituents from a Gynostemma laxum and their antioxidant and neuroprotective activities

Authors: Ji Yeon Seo, Sang Kyum Kim, Phi Hung Nguyen, Ju Yong Lee, Pham Ha Thanh Tung, Sang Hyun Sung and Won Keun Oh Source: Seo et al. Chin Med (2017) 12:15 DOI 10.1186/s13020-017-0136-y Abstract: Background: A few bioactivities of constituents from Gynostemma laxum, which has been collected in Vietnam, have been reported until now. There is no report about the effects of constituents from G. laxum although the nuclear factor (erythroid-derived 2)-like 2 (Nrf2)-mediated heme oxygenase-1 (HO-1) antioxidant defense system is involved in neuroprotection in the brain. Therefore, we investigated whether…

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